Prevalence of Aminoglycoside Resistance Genes in Acinetobacter baumannii Isolates

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Prevalence of Aminoglycoside Resistance Genes in Acinetobacter baumannii Isolates

BACKGROUND Acinetobacter baumannii is one of the major causes of nosocomial infections and is resistant to most available antibiotics. Aminoglycosides remain as drugs of choice for treatment of Acinetobacter infections yet resistance to aminoglycosides has increased in the recent years. OBJECTIVES The present study investigated the prevalence of genes encoding aminoglycoside-modifying enzymes...

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prevalence of aminoglycoside resistance genes in acinetobacter baumannii isolates

conclusions the results of this study indicated that the genes encoding aminoglycoside-modifying enzymes are prevalent in a. baumannii isolates in the study region, which highlighted the necessity of considering preventive measures to control dissemination of these resistance genes. results antimicrobial susceptibility analysis showed that the highest resistance was towards beta−lactam antibiot...

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Antibiotic Resistance Patterns and Prevalence of PER and VEB Resistance Genes among Clinical Isolates of ESBL-Producing Acinetobacter Baumannii

ABSTRACT          Background and Objectives: Acinetobacter species are responsible for a wide range of clinical complications in hospitalized patients. Antimicrobial treatment of clinical strains of Acinetobacter baumannii may be compromised due to multiple-drug resistance to b-lactams. Aim of this study was to determine antibiotic resistance patterns an...

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Association between mutations in gyrA and parC genes of Acinetobacter baumannii clinical isolates and ciprofloxacin resistance

Objective(s): We investigated the contribution of gyrA and parC mutational mechanism in decreased ciprofloxacin susceptibility of Acinetobacter baumannii isolated from burn wound infections. Materials and Methods: Ciprofloxacin susceptibility of 50 A. baumannii isolates was evaluated by disk diffusion and agar dilution methods. PCR and sequencing were performed for detection of mutation in gyr...

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Background & objective: Multidrug-resistant Acinetobacter baumannii (MDR-AB) is an important nosocomial pathogen which is associated with significant morbidity and mortality, particularly in high-risk populations. Aminoglycoside-modifying enzymes (AMEs) and 16S ribosomal RNA (16S rRNA) methylation are two important mechanisms of resistance to ...

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ژورنال

عنوان ژورنال: Jundishapur Journal of Microbiology

سال: 2014

ISSN: 2008-3645,2008-4161

DOI: 10.5812/jjm.11924